For those who are experiencing crashes, this tool will likely fix the issue:
Quote: “This small tool patches x86 executables in order to let them have 4GB (instead of only 2) of virtual memory on x64 platforms. This is handy for applications which need a larger amount of virtual memory like games, 3D renderization, multimedia etc.”
And the file you need to patch is typically found here:
C:\Program Files (x86)\Steam\SteamApps\common\Resident Evil 4\Bin32\bio4.exe
The patch tool will automatically create a backup file, so the original bio4.exe won’t be lost.
Thus far those who have patched the exe file have no longer experienced crashes. We hope this helps anyone else having a similar issue!